This is an interesting question, and there aren't really any firm guidelines. On the one hand, it's true that certain colors might not work well in a given room if there is a strong color theme already established. On the other, many feel that the art alone should drive the selection of a mat and frame, and that clashing colors should be disregarded. Another consideration is the fact that a particular piece may not remain in a certain room, making the original deliberations about color and matching all moot. Of course, coordinating color, even in mats and frames, may be an artistic pursuit for an entire room, thus "going back to square one." There are endless possibilities for matting and frames both, and we can help help you choose something that will work perfectly, considering all factors.